John Hockenbarry interviewed Kurt Vonnegut on "the Infinite Mind" series. It's available free on an interesting site (if you like podcasts and Google videos): Learn Out Loud. This broadcast is in "Second Life": a virtual community (but, of course, Vonnegut--through his virtual avatar--professes to be a Luddite).
It's also available as a podcast (by going to the Infinite Mind site, rather than Learn Out Loud, which will take you to Google video/Second Life).
This is said to be Vonnegut's last interview, but I can't find out when it was recorded.